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J Shahrekord Univ Med Sci. 2022;24(3): 111-116.
doi: 10.34172/jsums.2022.18
  Abstract View: 539
  PDF Download: 307

Original Article

Comparing the effects of ropivacaine and lidocaine associated with epinephrine on the heart rate, blood pressure, and amount of bleeding in patients candidate for cleft palate repair: A randomized clinical trial

Ahmad Eghbali 1 ORCID logo, Bahram Khoram 2* ORCID logo

1 Department of Anesthesiology, School of Medicine Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Department of Anesthesiology, School of Medicine, Kashani Hospital Shahrekord University of Medical Sciences, Tehran, Iran
*Corresponding Author: *Corresponding Author: Bahram Khoram, Email: , Email: bahramkhorram2021@gmail.com

Abstract

Background and aims: This study was conducted to compare the effects of two compounds ropivacaine and lidocaine associated with epinephrine on the heart rate, blood pressure, and bleeding rate in children undergoing general anesthesia for the cleft palate repair surgery.

Methods: In this study, 30 children candidates for cleft palate surgery who were referred to Mofid Children’s Hospital, affiliated with Shahid Beheshti University of Medical Sciences in 2021, were included by using the convenience sampling method. The patients were randomly divided into two groups. Group 1 was treated with ropivacaine and group 2 was treated with lidocaine along with epinephrine. The data were analyzed by the SPSS, version 22.

Results: In total, no statistically significant difference was found between the two groups in terms of vital signs of blood pressure and heart rate in the 10 stages studied (P<0.05). There was no difference between the two groups in the trend of the changes in blood pressure (P=0.381) and heart rate (P=0.940). However, the trend of blood pressure and heart rate had significantly changed during the study in both groups individually (P<0.001). The bleeding rate (suction) (P<0.001) and the weight of gases used (P=0.003) in the second group were significantly higher than in the first group.

Conclusion: No difference was found between the effects of ropivacaine and lidocaine combined with epinephrine on the heart rate and blood pressure in patients who were candidates for the cleft palate surgery, but the rate of bleeding (suction) in the second group was more than the first group.

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Abstract View: 540

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Submitted: 29 Sep 2021
Revision: 11 Dec 2021
Accepted: 12 Dec 2021
ePublished: 18 Aug 2022
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