Abstract
Background and aim: Contrast-induced nephropathy (CIN) is a common and serious complication related to intravenous injection of iodinated contrast media. So, the aim of this study was the evaluation of CIN frequency and the relationship of some variables with CIN in the patients that were referred to Hajar Hospital, Shahrekord, Iran. Methods: The study was done on 200 patients who were candidates for contrast-enhanced computed tomography (CECT) with intravenous contrast in 2018 in Shahrekord, Iran. Metformin and non-steroid anti-inflammatory drugs were discontinued from 48 hours before to 48 hours after contrast prescription. Almost 100 ml, of nonionic, iso-osmolar contrast media (Visipaque or Discopaque) were used for the patients. After 48 hours of contrast injection, blood urea nitrogen (BUN) and serum Creatinine (Cr) were checked and data were collected. Cr rising > 0.3mg/dl of baseline was considered Acute kidney injury (AKI) and Cr rising >0.5mg /dl was considered CIN. Results: Mean age of the patients were 63.65 ± 20 years. The mean serum Creatinine (Cr) of the patients before and after the contrast injection were 1.13±0.83mg/dl and 1.10±0.72mg/dl respectively (P=0.44). The frequency of AKI nephropathy (serum Cr rising >0.3mg/dl) was 11.5% (23 cases), however with serum Cr rising of 0.5 mg/dl, it was 4.5% (9 cases). Only the age of the patients was found a risk factor for CIN. Conclusion: CIN was not common in cases with normal or near normal renal function, however in old age patients contrast prescription should be done more carefully.