Shahrekord University of Medical Sciences Journal of Shahrekord University of Medical Sciences 2717-0071 28 1 2026 04 20 Personality Traits, Emotional Intelligence, and Sexual Functioning in Women With Metastatic and Non-Metastatic Breast Cancer: A Comparative Study 29 36 10.34172/jsums.1096 EN Fatemeh Moghtadaie Rad https://orcid.org/0009-0000-8744-2802 Fatemeh Sadeghi https://orcid.org/0000-0002-9840-231X Hamid Reza Mirzaei https://orcid.org/0000-0003-0218-9460 Journal Article 10.34172/jsums.1096 2025 08 16 2025 10 14 Background and aims: Psychological and functional aspects, such as personality traits, emotional intelligence (EI), and sexual functioning, are critical yet often overlooked in women with breast cancer (BC). Thus, this study compared these variables between metastatic and non-metastatic patients. Methods: In this cross-sectional study, 150 young married women diagnosed with BC (metastatic and non-metastatic) were recruited from Shohadaye Tajrish Hospital in Tehran in 2024 through purposive sampling. Data were collected using the NEO-Five Factor Inventory (1992), Bar-On Emotional Intelligence Questionnaire (2003), and Female Sexual Function Index (2000). Statistical analysis was conducted in SPSS 27 using descriptive statistics, multivariate analysis of variance, and independent t-tests. Results: Univariate ANOVAs revealed significant differences between groups in personality traits: neuroticism (F (1,148)=5.68, P=0.018, η²=0.037), extraversion (F (1,148)=26.17, P<0.001, η²=0.150), and conscientiousness (F (1,148)=10.45, P=0.002, η²=0.066), with non-metastatic patients scoring higher in extraversion and conscientiousness. Similarly, significant differences were found in interpersonal skills (F (1,148)=40.64, P<0.001, η²=0.215) and sexual functioning, including arousal (F (1,148)=51.61, P<0.001, η²=0.259) and satisfaction (F (1,148)=53.05, P<0.001, η²=0.264), with non-metastatic patients reporting higher scores. Conclusion: It was revealed that disease stage in BC correlates with distinct psychological and sexual health profiles. Accordingly, integrating psychosocial interventions into oncology care for metastatic patients may enhance emotional well-being and quality of life.