Shahrekord University of Medical Sciences Journal of Shahrekord University of Medical Sciences 2717-0071 22 3 2020 06 29 Description and management of non-metastatic thoracic myxofibrosarcoma: a case report 151 154 10.34172/jsums.2020.24 EN Amir Hossein Aalami https://orcid.org/0000-0003-4928-254X Amir Amirabadi https://orcid.org/0000-0001-9978-4359 Fatemeh Hosseini Mojahed https://orcid.org/0000-0002-7118-2986 Ali Ayatllahi https://orcid.org/0000-0001-9718-1845 Journal Article 10.34172/jsums.2020.24 2020 01 01 2020 02 08 Myxofibrosarcoma is a soft tissue sarcoma (STS) prevailing in the elderly and is associated with metastasis and mortality. In this case, an 88-year-old male is presented with a progressively enlarging mass in the posterior thorax. The physical examination revealed a solid, irregular, painful mass on palpation. Doppler ultrasonography and high-resolution computed tomography (CT) scan revealed a 60 × 38 mm hypoechoic tumor in the left paraspinal thoracic area with a little vascularity with no adherence and invasion. Radical excisional surgery was performed. The histopathology findings were in line with myxofibrosarcoma except for CD34. He underwent high dose radiotherapy due to the reported not assessable margins at one side. The patient was asymptomatic and recurrent free in the 12 months follow up assessment. It was the first known case of the non-metastatic intermediate grade of myxofibrosarcoma in the thorax. Due to its deceptive findings, myxofibrosarcoma should always be considered in the assessment of chest wall tumors.