J Shahrekord Univ Med Sci. 2024;26(1): 39-41.
doi: 10.34172/jsums.732
  Abstract View: 221
  PDF Download: 140

Case Report

Ovarian Sertoli cell tumor: A rare case of sex cord stromal tumor in a three-year female

Kiavash Fekri 1 ORCID logo, Shima Rahmati 1* ORCID logo

1 Cancer Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
*Corresponding Author: Shima Rahmati, Email: rahmati.sh@skums.ac.ir


Sertoli–Leydig cell tumors (SLCTs), also known as androblastoma, are rare, accounting for less than 1% of ovarian neoplasms. The clinical manifestations of SLCT range from asymptomatic to severe virilization. The majority of Sertoli cell tumors are highly differentiated, with homogeneous nuclei and few mitotic signs among the neoplastic cells. This study is a case report of a 3-year-old girl who was admitted to Kashani hospital with abdominal pain and a protruding stomach. On the right side of the abdomen, there was a large, lump palpable. Inhibin, calretinin, actine, and WT1 were all detected as positive by immunohistochemistry (IHC) testing. However, CD30, NSE, synaptophysin, vimentin, chromogranin, S100, and AFP were all detected to be negative. Additional information about ovarian sex cord tumors is provided in this case. Sertoli cell tumor should be considered a differential diagnosis in a young girl who has hirsutism, irregular bleeding, and breast atrophy with a pelvic mass.
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Submitted: 27 Jun 2022
Revision: 01 Aug 2022
Accepted: 02 Aug 2022
ePublished: 31 Oct 2023
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