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J Shahrekord Univ Med Sci. 2022;24(3): 139-144.
doi: 10.34172/jsums.2022.23
  Abstract View: 791
  PDF Download: 451

Original Article

The relationship between acute cardiac attack and LDL-C serum levels in cardiac and CCU inpatients in Hajar hospital: Replying to a paradox

Masoud Lotfizadeh 1 ORCID logo, Arsalan Khaledifar 2* ORCID logo, Foroogh Heidari 3 ORCID logo, Abdolvahab Khademi 4 ORCID logo

1 Social Determinants of Health Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
2 Modeling in Health Research Center, Department of Cardiology, Hajar Hospital, School of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
3 School of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
4 Department of Measurement & Statistics, University of Massachusetts, Amherst, Massachusetts, USA
*Corresponding Author: *Corresponding Author: Arsalan Khaledifar, Hajar Hospital, School of Medicine, Shahrekord University of Medical Sciences, Email: khaledifar.ar.dr@gmail.com, , Email: khaledifar@skums.ac.ir

Abstract

Background and aims: Acute myocardial infarction (MI) is one of the most prevalent heart diseases across the world, including in Iran. The purpose of the present study was to investigate the relationship between acute MI and serum low-density lipoprotein (LDL) levels in patients with acute MI.

Methods: In this descriptive-inferential study, 1274 MI patients hospitalized in Shahrekord Hajar Hospital were selected using the census method. The required information was drawn from the patient’s medical records according to inclusion criteria. Statistical analyses were performed using analysis of variance (ANOVA) and chi-square test to examine the relationship between the LDL level and awareness in patients.

Results: In this study, the average age of patients with acute heart attack was 13.79±63.18 years. Of the 1274 studied patients, 78% (999 people) were men and the rest were women. In both male and female genders, most patients had LDL levels between 70 and 129 mg/dL. Regarding statin use, 757, 287, and 162 people had a history of statin use, hypertension (HTN), and cardiovascular disease, respectively. In addition, 150 and 152 people had diabetes and a history of smoking, respectively. In this study, a significant relationship was found between the history of statin use (P<0.0001) and the frequency of MI (P=0.049) in LDL groups.

Conclusion: The results of this research revealed a significant relationship between LDL groups and the number of times acute heart attack occurs as a long-term complication in people who have had one.

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Submitted: 27 Jun 2022
Revision: 20 Jul 2022
Accepted: 20 Jul 2022
ePublished: 18 Aug 2022
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